With so many complaints of physique aches, researchers from a 2022 examine revealed in The Lancet took an in-depth have a look at the causes of affected person muscle aches and whether or not they may actually be traced to the remedy. In analyzing information from 23 completely different medical trials, the examine staff discovered that almost all of body-ache circumstances weren’t really on account of statin use. Whereas it was discovered that statins did yield a 7% enhance in affected person muscle signs, this hyperlink was noticed principally throughout the first 12 months of therapy, and the discomfort was normally delicate. Sufferers who reported the event of muscle aches past the primary 12 months of therapy have been predominantly prescribed extra intensive statin remedy. Total, greater than 90% of muscle-ache circumstances have been discovered to be unrelated to statin use.
Commenting on these findings, joint lead creator on the examine professor Colin Baigent instructed the College of Oxford, “Our analysis exhibits that, for most individuals taking a statin, any muscle-related signs they expertise is not going to actually be as a result of statin itself – and so the potential advantages of statin remedy are more likely to outweigh the muscle ache dangers.” Baigent went on so as to add that any research indicating statins to be the definitive reason behind physique aches are doubtless flawed in design.