“What we principally discovered is that centenarians manifest a historical past of publicity to pure environmental immunogens that made them extra resilient and extra proof against potential dangerous components,” co-researcher on the examine Dr. Stefano Monti instructed HealthDay. Not solely that, however the examine crew additionally recognized the heightened expression of 1 specific gene related to combating off DNA harm as a think about longevity.
Whereas the analysis could probably shed some gentle on one issue that will contribute to a protracted lifespan, some consultants state that there are too many confounding variables that contribute to longevity, subsequently making it tough to isolate causation. This may embody household medical historical past, wholesome life-style habits, and extra.
Even so, different consultants really feel inspired by the findings, stating how the knowledge could assist inform developments in future therapies to permit sufferers to take pleasure in many extra years to return. “If we will decide what’s creating this immune resilience for many who stay over 100, that may result in remedies that may assist folks stay longer,” senior director of the Nationwide Council on Getting old’s Middle for Wholesome Getting old, Kathleen Cameron, instructed Medical Information Right now in response to the analysis findings.