A 2022 systematic evaluate in Frontiers in Vitamin pooled the consequences of berberine from 49 analysis research. Total, berberine can cut back ldl cholesterol and triglycerides, insulin, physique mass index (BMI), waist circumference, and weight. Nonetheless, in case you have a BMI of lower than 25, berberine was ineffective for all of those outcomes. Even for folks whose BMI is above 25, the load change was lower than two kilos and BMI was about 1/4 of a degree. In reality, integrative medication specialist Dr. Melinda Ring tells The New York Instances that the consequences of berberine on weight reduction are “grossly overstated.”
Like Ozempic, berberine additionally comes with gastrointestinal negative effects resembling diarrhea and an upset abdomen, in response to The Dialog. As a result of berberine might permeate the placenta and hurt an unborn fetus, it is not beneficial for those who’re pregnant or breastfeeding. Berberine additionally might work together with drugs for blood clots, diabetes, and hypertension (through WebMD). Dietary supplements resembling berberine aren’t regulated by the Meals and Drug Administration, as per CBS Information, so the quantity of berberine in a bottle may not be what’s acknowledged on the label.